Mike Davis lives in Oklahoma, but he has traveled to Alaska many times to work with our greatest athletes.

Davis, an Oklahoma State University veterinarian and exercise physiologist has many times traveled to Alaska for the start of the Iditarod. There, he has cheered on Aliy Zirkle, Martin Buser and other mushers who have over the years entrusted Davis to take blood and muscle samples from their dogs.

Davis’s goal is to discover the magic within a sled dog that allows it to keep going and going. While we humans tend to fade after exercising just a few hours, sled dogs are somehow able to avoid that crash.

“Dogs will go from using their reserves to not (using reserves) in 48 hours,” Davis said. “They gain fitness that fast. Their response is to change their metabolism so they don’t use up their reserves anymore.”

Finding the trigger to that change is Davis’s big question. He is funded in part by the U.S. Army Research Office Division of Life Sciences, which is interested in improved performance of human beings.

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One factor Davis has studied is the performance of dogs that ran two 1,000-mile races in quick succession. For example, a majority of dogs that pulled Zirkle of Two Rivers from Willow to Nome in the 2012 Iditarod were the same dogs that had raced her husband Allen Moore to second place in the Yukon Quest less than three weeks earlier.

“They don’t just continue to perform, they perform a lot better,” Davis said of dogs that run both races. “There’s a good argument that nothing prepares a dog better for a 1,000-mile race than a 1,000-mile race. They can do it indefinitely, as long as you have trail and they’ve got food. They get tired, but they don’t fatigue in the biochemical sense.”

The key to a sled dog’s endurance is its ability to get energy it can use immediately. Davis and others have found that dogs are much quicker than us at moving energy into their muscles.

“The faster you can get stuff into a muscle cell, the faster you can use it,” Davis said. “They may get better at pulling fat out of the bloodstream on the fly.”

The key to this ability is in a sled dog’s “transporters,” proteins that allow it to pull carbohydrates and fats through cell membranes and into muscle cells. The proteins we use for that job also exist in dogs, but Davis and other researchers found decreased numbers of the human-style transporters within dogs at a time when the measurements showed the dogs were moving more fat.

“Something is transporting the fat into dog muscle, but it isn’t the transporter that we use,” Davis said.

The mystery protein that ushers energy molecules across dogs’ cell membranes might be hiding from researchers not only because it’s different than the one we use, but because it might be so efficient that there are fewer of them to be found.

• Since the late 1970s, the University of Alaska Fairbanks’ Geophysical Institute has provided this column free in cooperation with the UAF research community. Ned Rozell ned.rozell@alaska.edu is a science writer for the Geophysical Institute. A version of this column ran in 2012.